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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL1
All Species:
20.3
Human Site:
Y37
Identified Species:
29.78
UniProt:
Q9UBP6
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP6
NP_005362.3
276
31471
Y37
M
A
D
H
T
L
R
Y
P
V
K
P
E
E
M
Chimpanzee
Pan troglodytes
XP_001167352
301
34100
Y62
I
A
D
H
T
L
R
Y
P
V
K
P
E
E
M
Rhesus Macaque
Macaca mulatta
XP_001116496
301
34160
Y62
M
A
D
H
T
L
R
Y
P
V
K
P
E
E
M
Dog
Lupus familis
XP_849422
247
28132
K37
D
P
K
D
K
K
E
K
R
A
Q
A
Q
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z120
268
30585
S41
K
P
E
E
M
D
W
S
E
L
Y
P
E
F
F
Rat
Rattus norvegicus
XP_001054797
267
30550
S40
K
P
E
E
M
D
W
S
E
L
Y
P
E
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516298
226
25512
P24
L
F
P
A
F
C
P
P
L
T
K
Q
E
E
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU94
273
31824
Y39
M
A
D
H
T
F
Q
Y
P
V
K
P
E
V
M
Zebra Danio
Brachydanio rerio
Q5XJ57
241
27917
S37
C
P
E
Q
M
D
W
S
P
L
Y
P
Q
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77263
256
29406
R38
Q
K
R
Y
Y
R
Q
R
A
H
S
N
P
I
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23126
256
30022
N37
Y
R
Q
R
A
H
S
N
P
H
S
D
H
D
I
Sea Urchin
Strong. purpuratus
XP_790960
406
47124
H103
K
N
N
T
S
S
P
H
D
L
Y
P
K
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
B6SHG7
255
29101
I37
D
S
H
F
P
V
P
I
S
P
E
E
V
D
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXB7
251
28800
I38
L
S
D
S
H
F
P
I
P
I
S
P
A
H
V
Baker's Yeast
Sacchar. cerevisiae
Q12009
286
33373
K44
S
L
V
Q
E
G
Q
K
I
D
L
P
K
K
R
Red Bread Mold
Neurospora crassa
Q7RZC1
293
33715
Y48
F
S
D
H
S
L
I
Y
P
P
T
P
E
Q
M
Conservation
Percent
Protein Identity:
100
90.6
90.6
81.5
N.A.
88
88.4
N.A.
64.8
N.A.
69.5
67.7
N.A.
47.4
N.A.
50.7
42.3
Protein Similarity:
100
91.3
91
83.6
N.A.
92.3
90.9
N.A.
72
N.A.
80
76.4
N.A.
59.7
N.A.
64.8
51.2
P-Site Identity:
100
93.3
100
0
N.A.
13.3
13.3
N.A.
20
N.A.
80
13.3
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
26.6
26.6
N.A.
26.6
N.A.
86.6
33.3
N.A.
13.3
N.A.
20
46.6
Percent
Protein Identity:
N.A.
52.5
N.A.
50
46.8
48.8
Protein Similarity:
N.A.
68.4
N.A.
68.4
61.5
66.2
P-Site Identity:
N.A.
0
N.A.
20
6.6
53.3
P-Site Similarity:
N.A.
33.3
N.A.
46.6
26.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
7
7
0
0
0
7
7
0
7
7
0
7
% A
% Cys:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
38
7
0
19
0
0
7
7
0
7
0
13
0
% D
% Glu:
0
0
19
13
7
0
7
0
13
0
7
7
50
25
13
% E
% Phe:
7
7
0
7
7
13
0
0
0
0
0
0
0
13
19
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
7
32
7
7
0
7
0
13
0
0
7
7
0
% H
% Ile:
7
0
0
0
0
0
7
13
7
7
0
0
0
7
13
% I
% Lys:
19
7
7
0
7
7
0
13
0
0
32
0
13
7
0
% K
% Leu:
13
7
0
0
0
25
0
0
7
25
7
0
0
0
7
% L
% Met:
19
0
0
0
19
0
0
0
0
0
0
0
0
0
32
% M
% Asn:
0
7
7
0
0
0
0
7
0
0
0
7
0
0
0
% N
% Pro:
0
25
7
0
7
0
25
7
50
13
0
69
7
0
0
% P
% Gln:
7
0
7
13
0
0
19
0
0
0
7
7
13
7
0
% Q
% Arg:
0
7
7
7
0
7
19
7
7
0
0
0
0
0
7
% R
% Ser:
7
19
0
7
13
7
7
19
7
0
19
0
0
7
0
% S
% Thr:
0
0
0
7
25
0
0
0
0
7
7
0
0
0
0
% T
% Val:
0
0
7
0
0
7
0
0
0
25
0
0
7
13
7
% V
% Trp:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
7
0
0
32
0
0
25
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _